NCT06852313Recruiting
Save the Ovaries - Surgical Management of Simple Ovarian Cysts in Children and Adolescents
Summary
The purpose of this study is to evaluate which operative technique should be used for managing simple ovarian cysts in girls and adolescents. The two techniques that are being compared are laparoscopic cyst enucleation and laparoscopic cyst deroofing. The investigators will assess the effect of both techniques on the ovarian reserve and the risk of cyst recurrence.
Inclusion criteria
• Symptomatic simple cysts ≥ 4 cm with indication for surgical intervention • Asymptomatic cysts ≥ 4 cm, with surgical indication due to persistence or increase in size • Asymptomatic cysts ≥ 4 cm with other pathology as surgical indication, if known preoperatively • Age 12 months - 18 years • Parents/legal custodian and patient give consent, for patients unable to consent due to their health condition or developmental status they show no signs of unwillingness to participate • Symptomatic simple cysts ≥ 4 cm with indication for surgical intervention on both ovaries (each ovary will count as one)
Exclusion criteria
• Neonatal ovarian cysts (age \<12 months) • Age \>18 years • Complex cysts (with solid components, e.g., Teratoma, risk or suspicion of malignancy) • Paratubar/paraovarian cysts • Medical reason that precludes cyst enucleation (e.g. severe coagulopathy) • Neither signed informed consent form or inadequate german, french or english language skills to give informed consent
Contacts
The trial team's contact details are shown on request.
See the official trial record- Status
- Recruiting
- Phase
- No phase (N/A)
- Study type
- Interventional
- Countries
- Switzerland
- Sponsor
- University Children's Hospital, Zurich(Other)
- Protocol no.
- SAVEOVPRO2025
- Conditions
- Ovarian Cyst Benign
- Interventions
- Procedure
Treatments studied
- Laparoscopic ovarian cyst surgery
Collaborators
University Children's Hospital Basel
Locations · 2
- Basel, SwitzerlandUniversity Children's Hospital BaselRecruiting at this site
- Zurich, SwitzerlandUniversity Children's Hospital ZurichRecruiting at this site
In total, worldwide, both sites listed in the registry are recruiting.
Site status per the ClinicalTrials.gov registry (last update posted: April 28, 2026).
This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.
See also
Other versions
These results are indicative and do not replace medical advice — discuss them with your doctor.