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NCT07096258Recruiting

EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients

Official recordSimplified version

Summary

The goal of this registry is to capture real-world data from plasma- and tissue-based molecular profiling, treatments, outcomes and patient-reported outcomes from patients with advanced or metastatic non-small cell lung cancer (NSCLC). The main objective of the study is to better understand the real-world clinical practice of the use and utility of molecular tumour profiling, the choice of treatment, and the outcome after such molecular profiling and treatment.

Inclusion criteria

• Locally advanced or metastatic, unresectable NSCLC, stages IIIB/C or IV, who have not previously been treated for this advanced disease. • Intention-to-initiate first-line tumour therapy for this advanced disease. • Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2. • At least 18 years of age on the day of signing informed consent, and capable of signing informed consent.

Exclusion criteria

• Any known non-cutaneous malignancy (except for this NSCLC and early-stage non-invasive cervical cancer) that has occurred within 5 years prior to enrolment.

Contacts

The trial team's contact details are shown on request.

See the official trial record
Status
Recruiting
Phase
—
Study type
Observational
Countries
Switzerland, France, Italy, Spain
Sponsor
Hedera Dx SA(Industry)
Protocol no.
EMPATHY NSCLC
Conditions
NSCLC (Advanced Non-small Cell Lung Cancer)
Interventions
—

Locations · 3

  • Geneva, SwitzerlandHôpitaux Universitaires GenèveRecruiting at this site
  • Nancy, FranceUniversité de LorraineRecruiting at this site
  • Naples, ItalyUniversity of Naples "Federico II"Recruiting at this site

In total, worldwide, 3 of the 4 sites listed in the registry are recruiting; the other one is not currently recruiting.

Site status per the ClinicalTrials.gov registry (last update posted: July 31, 2025).

This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.

See also

Other versions

These results are indicative and do not replace medical advice — discuss them with your doctor.