NCT07112196Recruiting
Visugromab in Cachexia International Trial
Summary
A study of how well and safely a new drug called visugromab works in people with certain kinds of cancer (including lung and bowel cancer) and unintended weight loss known as cachexia. The main questions it aims to answer are: * Does visugromab help participants put weight back on and have a better appetite? * Does visugromab help participants move more and better? * What medical problems do participants have when taking visugromab? Researchers will compare visugromab to a placebo (a look-alike substance that contains no drug). Participants will visit the hospital or clinic once every 4 weeks to receive visugromab or placebo via a drip into a vein and to undergo checkups and tests.
Inclusion criteria
• Weight loss • Advanced cancer
Exclusion criteria
• Participation in another interventional clinical trial, receipt of any investigational therapy or use of any investigational device within 4 weeks prior to screening and between screening and the first dose of investigational product
Contacts
The trial team's contact details are shown on request.
See the official trial record- Status
- Recruiting
- Phase
- Phase 2 · Phase 3
- Study type
- Interventional
- Countries
- Switzerland, France, Germany, Italy, United States, Bulgaria, Czechia, Norway, Poland, Romania, Spain, United Kingdom
- Sponsor
- CatalYm GmbH(Industry)
- Protocol no.
- CTL-002-006
- Conditions
- Cancer-associated Cachexia
- Interventions
- Drug
Treatments studied
- Visugromab (CTL-002)
- Placebo
- Visugromab (CTL-002)
- Visugromab (CTL-002)
Locations · 74
- Aarau, SwitzerlandTumor Zentrum AarauRecruiting at this site
- Basel, SwitzerlandUniversitaetsspital BaselRecruiting at this site
- Bellinzona, SwitzerlandIstituto Oncologico della Svizzera ItalianaRecruiting at this site
- Lugano, SwitzerlandGruppo Ospedaliero Moncucco - Clinica MoncuccoRecruiting at this site
- Sankt Gallen, SwitzerlandCantonal Hospital St. Gallen (Kantonsspital St. Gallen)Recruiting at this site
- Zurich, SwitzerlandUniversity Hospital of Zurich (Universitätsspital Zürich)Recruiting at this site
- Brest, FranceCHRU de Brest - Hopital MorvanRecruiting at this site
- Créteil, FranceAP-HP Hôpital Henri MondorRecruiting at this site
- Lyon, FranceLéon Bérard Center (Centre Léon Bérard)Recruiting at this site
- Lyon, FranceHCL Centre Hospitalier Lyon SudRecruiting at this site
- Strasbourg, FranceCentre Paul StraussRecruiting at this site
- Bonn, GermanyJohanniter Krankenhaus BonnRecruiting at this site
- Dresden, GermanyUniversity Hospital Carl Gustav Carus Dresden (Universitätsklinikum Carl Gustav Carus Dresden)Recruiting at this site
- Großhansdorf, GermanyLungenClinic Grosshansdorf GmbHRecruiting at this site
- München, GermanyMuenchen Klinik NeuperlachRecruiting at this site
- Aviano, ItalyCentro Riferimento Oncologico - AvianoRecruiting at this site
- Brescia, ItalyASST degli Spedali Civili di BresciaRecruiting at this site
- Ferrara, ItalyAzienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'AnnaRecruiting at this site
- Meldola, ItalyIRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l.Recruiting at this site
- Verona, ItalyCentro Ricerche Cliniche di VeronaRecruiting at this site
- Norwich, United StatesEastern Connecticut Hematology & OncologyRecruiting at this site
- Clermont, United StatesClermont Oncology CenterRecruiting at this site
- Orange City, United StatesMid Florida Hematology and Oncology CentersRecruiting at this site
- Stuart, United StatesCleveland Clinic Martin HealthRecruiting at this site
- Augusta, United StatesAugusta University Medical CenterRecruiting at this site
- East Brunswick, United StatesAstera Cancer CareRecruiting at this site
- Avon, United StatesCleveland Clinic Avon HospitalRecruiting at this site
- Cleveland, United StatesCleveland Clinic (Main Campus)Recruiting at this site
- Fairview, United StatesCleveland Clinic Fairview HospitalRecruiting at this site
- Mayfield Heights, United StatesCleveland Clinic Hillcrest HospitalRecruiting at this site
In total, worldwide, all 74 sites listed in the registry are recruiting.
Site status per the ClinicalTrials.gov registry (last update posted: September 22, 2026).
This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.
+ 44 more locations
See also
Other versions
These results are indicative and do not replace medical advice — discuss them with your doctor.