NCT07699861Recruiting
LUCINAE Registry: Thoracic Cancers During Pregnancy
Summary
The LUCINAE Registry is an international, multicenter observational study collecting data on patients with thoracic cancers (including lung cancer) who are expecting a child. This includes women diagnosed during pregnancy, women who become pregnant during or after cancer, and men receiving cancer treatment at the time their partner conceives. Because thoracic cancers during pregnancy are rare, there is limited information to guide clinical decisions. This registry aims to describe patient characteristics, diagnostic approaches, treatments, and maternal and fetal outcomes. Data are collected retrospectively and prospectively from participating centers. The results of this registry are expected to improve understanding of thoracic cancers in this setting and support the development of future clinical recommendations.
Inclusion criteria
• 1\. All patients with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities) and pregnancy (positive pregnancy test) including: 1. Patients receiving a diagnosis of thoracic cancer during pregnancy 2. Patients who became pregnant while having active thoracic cancer 3. Patients previously treated for a thoracic cancer and becoming pregnant in the 5 years following end of treatment OR Men with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities), who were undergoing active oncological treatment at the time their partner conceived their child. • 2\. Available information about pregnancy outcomes • 3\. Age ≥ 18 years
Exclusion criteria
• 1\. Patient missing data about thoracic cancer stage and diagnosis • 2\. For retrospective patients, documented refusal to the use of clinical data for research purposes
Contacts
The trial team's contact details are shown on request.
See the official trial record- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Countries
- Switzerland
- Sponsor
- Oncology Institute of Southern Switzerland(Other)
- Protocol no.
- LUCINAE Registry
- Conditions
- Lung Cancer, Thoracic Cancer, Cancer During Pregnancy
- Interventions
- —
Collaborators
Clinical Trial Unit Ente Ospedaliero Cantonale
Locations · 4
- Baden, SwitzerlandKantonsspital BadenRecruiting at this site
- Bellinzona, SwitzerlandIstituto Oncologico della Svizzera Italiana (IOSI)Recruiting at this site
- Geneva, SwitzerlandGeneva University Hospital (HUG)Recruiting at this site
- Winterthur, SwitzerlandKantonsspital WinterthurRecruiting at this site
In total, worldwide, all 4 sites listed in the registry are recruiting.
Site status per the ClinicalTrials.gov registry (last update posted: October 21, 2026).
This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.
See also
Other versions
These results are indicative and do not replace medical advice — discuss them with your doctor.