NCT03435796Recruiting
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Summary
This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T-cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one infusion of GM T cells will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.
Inclusion criteria
• Received at least one gene-modified (GM) T-cell infusion in a previous Celgene sponsored, Juno Therapeutics, other affiliates of BMS, or Celgene alliance partner-sponsored trial, and have discontinued, or completed the post-treatment follow-up period in the parent treatment protocol, as applicable. • Must understand and voluntarily sign an Informed Consent Form/Informed Assent Form prior to any study-related assessments/procedures being conducted.
Exclusion criteria
Not Applicable Other protocol-defined inclusion/exclusion criteria apply
Contacts
The trial team's contact details are shown on request.
See the official trial record- Status
- Recruiting
- Phase
- Phase 2 · Phase 3
- Study type
- Interventional
- Countries
- Switzerland, France, Germany, Italy, Austria, United States, Australia, Belgium, Canada, Denmark, Finland, Greece, Israel, Japan, Netherlands, Norway, Poland, Romania, South Korea, Spain, Sweden, United Kingdom
- Sponsor
- Celgene(Industry)
- Protocol no.
- GC-LTFU-001
- Conditions
- Neoplasms
- Interventions
- Genetic
Treatments studied
- Gene-modified (GM) T cell therapy
Locations · 173
- Bern, SwitzerlandInselspital BernRecruiting at this site
- Creteil-Paris, FranceHopital Henri MondorRecruiting at this site
- Lille, FranceCHRU de Lille FranceRecruiting at this site
- Montpellier, FranceCentre Hospitalier Regional Universitaire (CHRU) Montpellier Arnaud de VilleneuveRecruiting at this site
- Montpellier, FranceCHU Montpellier - Hôpital Saint EloiRecruiting at this site
- Nantes, FranceChu Hotel DieuRecruiting at this site
- Paris, FranceHopital Saint LouisRecruiting at this site
- Paris, FranceHôpitaux Universitaires Pitie Salpêtrière Charles FoixRecruiting at this site
- Paris, FranceHospital Saint LouisRecruiting at this site
- Pessac, FranceCentre Hospitalier Universitaire (CHU) de Bordeaux - Hopital Haut-LevequeRecruiting at this site
- Pierre-Bénite, FranceCentre Hospitalier Lyon-SudRecruiting at this site
- Poitiers, FranceCHU La MiletrieRecruiting at this site
- Rennes, FranceHopital SudRecruiting at this site
- Toulouse, FranceInstitut Universitaire du Cancer de Toulouse - OncopoleRecruiting at this site
- Villejuif, FranceGustave RoussyRecruiting at this site
- Berlin, GermanyCharite-Universitaetsmedizin Berlin - Campus Charite Mitte (CCM)Recruiting at this site
- Berlin, GermanyRobert-Rossle-Klinik im HELIOS Klinikum Berlin-Buch Klinik fur Hamatologie, Onkologie u. TumorimmunoRecruiting at this site
- Cologne, GermanyKinikum der Universitaeat zu KoelnRecruiting at this site
- Dresden, GermanyUniversitatsklinikum Carl Gustav Carus an der TU DresdenRecruiting at this site
- Düsseldorf, GermanyUniversitaetsklinikum DuesseldorfRecruiting at this site
- Essen, GermanyUniversitaetsklinikum EssenRecruiting at this site
- Hamburg, GermanyUniversitaetsklinikum Hamburg-EppendorfRecruiting at this site
- Heidelberg, GermanyUniversitatsklinikum HeidelbergRecruiting at this site
- Magdeburg, GermanyOtto-von-Guericke-Universitaet Magdeburg - Universitaetsklinikum Magdeburg A.Oe.R - UniversitaetskliRecruiting at this site
- München, GermanyLMU Klinikum der UniversitätRecruiting at this site
- Ulm, GermanyUniversity Hospital of UlmRecruiting at this site
- Würzburg, GermanyUniversitatsklinikum Wurzburg Medizinische Klinik und Poliklinik IIRecruiting at this site
- Ancona, ItalyOspedali Riuniti di AnconaRecruiting at this site
- Bologna, ItalyAzienda Ospedaliero Universitaria Di Bologna Policlinico Sorsola MalpighiRecruiting at this site
- Milan, ItalyFondazione IRCCS Istituto Nazionale dei TumoriRecruiting at this site
In total, worldwide, 173 of the 222 sites listed in the registry are recruiting; the other 49 are not currently recruiting.
Site status per the ClinicalTrials.gov registry (last update posted: September 18, 2026).
This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.
+ 143 more locations
Other identifiers
- U1111-1206-8250 · other registry
- 2023-504201-36 · other identifier
- 2023 · NIH grant
See also
Other versions
These results are indicative and do not replace medical advice — discuss them with your doctor.