Cancer clinical trials in Bern
109 open trials with at least one site in Bern, according to ClinicalTrials.gov, updated on October 28, 2026.
These results are indicative and do not replace medical advice — discuss them with your doctor.
Open trials
- Reduced-dose Carboplatin-doublet-chemotherapy + Cemiplimab vs Cemiplimab Monotherapy in Treatment Naive Older and Frail Patients With Metastatic NSCLC With PD-L1 <50%
NCT07020065RecruitingPhase 2
- Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
NCT04728893RecruitingPhase 2
- A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
NCT05623020RecruitingPhase 3
- OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy
NCT06466382Recruiting
- MELCHRONO: A Prospective Randomized Study Investigating Chrono-immunotherapy for Advanced Melanoma.
NCT07574047RecruitingPhase 2
- Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.
NCT07593482RecruitingPhase 2
- A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
NCT06499285RecruitingPhase 3
- Swiss 2024 Continous Fever Monitoring in Pediatric Oncology Patients
NCT05940766Recruiting
- Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
NCT06463587RecruitingPhase 3
- A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
NCT07213674RecruitingPhase 3
- AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
NCT07611110RecruitingPhase 3
- PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
NCT04790253Recruiting
- Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
NCT07140172Recruiting
- A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
NCT07318558RecruitingPhase 3
- Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
NCT06401980RecruitingPhase 2
- A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
NCT07284849RecruitingPhase 3
- Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell Carcinoma
NCT06563362RecruitingPhase 2
- Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)
NCT07223814RecruitingPhase 3
- A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
NCT07522073RecruitingPhase 3
- Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
NCT05243797RecruitingPhase 3
- A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma
NCT06091254RecruitingPhase 3
- Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
NCT05902169RecruitingPhase 3
- A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
NCT06760819RecruitingPhase 2
- A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT06973187RecruitingPhase 3
- This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
NCT06758401RecruitingPhase 3
- A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL
NCT05748171RecruitingPhase 2
- Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
NCT06780670RecruitingPhase 2 · Phase 3
- Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
NCT03435796RecruitingPhase 2 · Phase 3
- Precise Chemoresection in Low-grade NMIBC Using Drug Screens in Patient-derived Organoids
NCT06227065Not yet recruitingPhase 2
- A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT06492616RecruitingPhase 3
- A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
NCT06615479RecruitingPhase 3
- Safety and Early Signs of Efficacy of IL12-L19L19.
NCT04471987RecruitingPhase 1
- Single-Fraction Very Accelerated Partial Breast Irradiation (sfVAPBI)
NCT07067437Recruiting
- Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
NCT06652438RecruitingPhase 3
- What Impact Does an Initial Psycho-oncological Contact Have on People With Cancer?
NCT07544446Recruiting
- Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer
NCT07058805RecruitingPhase 2
- Safety and Tolerability of IDO-1 Inhibition in the Prevention of EBV-related Pathology in EBV Negative Kidney Transplant Recipients Receiving an Organ From EBV Positive Donors
NCT07368153RecruitingPhase 2
- A Registry-study of ELZONRIS in Participants With BPDCN
NCT07785154Recruiting
- Best Salvage Treatment for High-risk Relapsing Prostate Cancer (PEACE-9 - ESCALATE-RT)
NCT07782112Not yet recruitingPhase 3
- ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer
NCT06801899Recruiting
- A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
NCT06203210RecruitingPhase 3
- Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning
NCT07415668Recruiting
- Impact of Gonadotoxic Therapies on Fertility
NCT05885048Recruiting
- Primary and Acquired Resistance to Targeted Treatment in BRAF V600E-mutated Metastatic Colorectal Cancer
NCT07617610Recruiting
- Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial
NCT05496998Recruiting
- Swiss Childhood Cancer Survivor Study
NCT03297034Recruiting
- Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial)
NCT07478536Not yet recruiting
- LITT for Ultra-early GBM Recurrence
NCT07616986Recruiting
- Cardiac Dysfunction in Childhood Cancer Survivors
NCT03790943Recruiting
- Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC
NCT05718323RecruitingPhase 2
- Pembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer
NCT05815927RecruitingPhase 3
- Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer
NCT06274879RecruitingPhase 2
- A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer
NCT06567782RecruitingPhase 2
- A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
NCT06284317RecruitingPhase 3
- Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland
NCT03124212Recruiting
- Early Pulmonary Dysfunction in Childhood Cancer Patients
NCT05427136Recruiting
- International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
NCT04043494RecruitingPhase 3
- Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance
NCT06936774RecruitingPhase 3
- Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy
NCT06249672Recruiting
- Questionnaire on Congenital Cancer Signs Through Self-Assessment
NCT07378423Recruiting
- Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
NCT05522660RecruitingPhase 3
- First in Human Study of T3P-Y058-739 (T3P)
NCT05120596RecruitingPhase 1 · Phase 2
- A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
NCT04988555RecruitingPhase 1 · Phase 2
- Resection of the Primary Tumor vs. Systemic Treatment Alone for Patients With Small Intestinal Neuroendocrine Tumors and Unresectable Metastases: a Europe-wide Study
NCT06787014Recruiting
- Trial of Preoperative Radiosurgery Versus Postoperative Stereotactic Radiotherapy for Resectable Brain Metastases
NCT05124236Recruiting
- Efficacy of the Combination of Trimipramine and Atezolizumab With Bevacizumab in Patients With Recurrent Glioblastoma: a Phase 2 Trial
NCT07263438RecruitingPhase 2
- Surgery for Recurrent Glioblastoma
NCT02394626RecruitingPhase 2
- Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)
NCT06835049RecruitingPhase 2
- Pragmatic Geriatric Assessment Before CAR-T or Bispecific Antibody Therapy to Predict Side Effects and Outcomes in Older Patients (GA-ACT Trial)
NCT07309497Recruiting
- The Development of MASLD Among Survivors of Breast or Colorectal Cancer
NCT07280143Recruiting
- The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
NCT05726786RecruitingPhase 3
- Metacognitive Intervention in Youth With Oncological Disease - the Mio Study
NCT06464237Recruiting
- VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer
NCT04057209Recruiting
- MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)
NCT04111978RecruitingPhase 3
- The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)
NCT04732273Recruiting
- Protoporphyrin Imaging in Multispectral Evaluation of Resections
NCT07021573Not yet recruiting
- A Multicenter, Prospective Study for Glioblastoma Patients
NCT07162324Not yet recruiting
- Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy
NCT07075016RecruitingPhase 3
- Safety & Feasibility of Ultrasound-assisted Non-invasive Measurement of Compressibility of the Thyroid Gland in Patients Scheduled for Surgical Removal
NCT07102264Recruiting
- Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
NCT06839794Recruiting
- OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)
NCT06462963Recruiting
- The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer
NCT05894070Recruiting
- SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours
NCT05192980Recruiting
- Restrictive Use of Dexamethasone in Glioblastoma
NCT04266977Recruiting
- Extended vs. No Pelvic Lymph Node Dissection During Radical Prostatectomy. DISSECTION 2.0.
NCT06776172Recruiting
- Skin Cancer and Hyperthermia and Radiotherapy
NCT06384053Recruiting
- Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
NCT06166706Recruiting
- Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
NCT03643276RecruitingPhase 3
- E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
NCT03818503Recruiting
- Swiss Severe Asthma Register
NCT03984253Recruiting
- EBV-Tscm Cytotoxic T Cells (CTLs) for EBV- Driven Lymphomas/ Diseases
NCT05688241Not yet recruitingPhase 1 · Phase 2
- Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)
NCT05017142Recruiting
- Discovery of New Cancer in the 1-year Follow-up After Ischemic Stroke in Patients at Risk: The INVISIBLE-1 Study
NCT06100718Recruiting
- Metabolic Characterization of Space Occupying Lesions of the Brain
NCT04233788Recruiting
- Intelligent Vacuum Assisted Biopsy Immediately Before Surgery As an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer
NCT04289935Recruiting
- Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)
NCT04498767Recruiting
- The Bern Rehab Registry
NCT06516172Recruiting
- Clinical Trial Investigating the Chemotherapeutic Compound Treosulfan (Trecondi® Ideogen) in Myeloma Patients
NCT05636787RecruitingPhase 2
- PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab)
NCT06430736RecruitingPhase 2
- Therapy-Associated Saliva and Taste Change Evaluation (TASTE) in Head & Neck Cancer Patients Undergoing Radiotherapy
NCT06444776Recruiting
- FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma
NCT04625907RecruitingPhase 1 · Phase 2
- Conebeam CT-based Online Adaptive Radio-Therapy for Esophageal Cancer (ARTEC)
NCT06361043Recruiting
- The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)
NCT06283927Recruiting
- The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)
NCT06118723Recruiting
- The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
NCT06273176Recruiting
- The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
NCT06146725Recruiting
- The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
NCT06146738Recruiting
- The European NAFLD Registry
NCT04442334Recruiting
- Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment
NCT04045691Recruiting