NCT06166706Recruiting
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Summary
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.
Inclusion criteria
• aged ≤ 16 years; • undergoing general anesthesia • airway management with tube or LMA; and • connected to mechanical ventilator . minimum duration of procedure: 15 minutes
Exclusion criteria
• patients undergoing surgical procedures involving extra-corporal circulation; • patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation; • sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and • (rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.
Contacts
The trial team's contact details are shown on request.
See the official trial record- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Countries
- Switzerland, Italy, Australia, Netherlands
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)(Other)
- Protocol no.
- C1_bigapple_V1.2
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Pulmonary Complication, Perioperative/Postoperative Complications
- Interventions
- —
Locations · 1
- Amsterdam, NetherlandsAmsterdam University Medical CentersRecruiting at this site
In total, worldwide, 1 of the 4 sites listed in the registry is recruiting; the other 3 are not currently recruiting.
Site status per the ClinicalTrials.gov registry (last update posted: April 9, 2025).
This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.
See also
Other versions
These results are indicative and do not replace medical advice — discuss them with your doctor.