NCT05192980Recruiting
SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours
Summary
The SIOPEN BIOPORTAL is a prospective non-therapeutic multi-centre international study aimed at developing an international Registry linked to a Virtual Biobank for all the patients with peripheral neuroblastic tumor within countries of the SIOPEN network. The overall aim of this study is to provide a GDPR-compliant framework to collect basic clinical annotations, biological and genetic features and information about the location on biospecimens for all the patients with a peripheral neuroblastic tumor including neuroblastoma, ganglioneuroblastoma and ganglioneuroma in the SIOPEN network. This study will support data and sample management and intensify cross-borders data and sample sharing fostering translational and clinical research. The post-hoc hypothesis formulated based on the data generated in this study will be used as statistical basis for future precision medicine programs based on improved biological characterization, patient stratification and therapeutic management.
Eligibility criteria
Inclusion Criteria: I-1. Patients with PNT: ganglioneuroma or ganglioneuroblastoma or neuroblastoma, I-2. At the time of initial diagnosis of neuroblastic tumour, or at relapse/progression if not yet registered I-3. Written patient informed consent, or parents or legal representative written informed consent and assent of the child, adolescent or young adult Non-Inclusion Criteria: R-1. (Adult) Patients with olfactory neuroblastoma R-2. Central nervous system (CNS) neuroblastoma (as per the WHO classification)
Contacts
The trial team's contact details are shown on request.
See the official trial record- Status
- Recruiting
- Phase
- No phase (N/A)
- Study type
- Interventional
- Countries
- Switzerland, France, Czechia, Norway
- Sponsor
- Institut Curie(Other)
- Protocol no.
- IC 2020-17
- Conditions
- Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma
- Interventions
- Other
Treatments studied
- No Intervention NA
Locations · 35
- Aarau, SwitzerlandKantonsspital Aarau AGRecruiting at this site
- Basel, SwitzerlandUniversitäts-Kinderspital beider Basel UKBBRecruiting at this site
- Bellinzona, SwitzerlandOspedale San GiovanniRecruiting at this site
- Bern, SwitzerlandInselspital BernRecruiting at this site
- Geneva, SwitzerlandHUG Hôpitaux Universitaires GenèveRecruiting at this site
- Lausanne, SwitzerlandCHUV, Centre hospitalier universitaire vaudoisRecruiting at this site
- Lucerne, SwitzerlandKinderspital Zentralschweiz, LuzernRecruiting at this site
- Sankt Gallen, SwitzerlandOstschweizer KinderspitalRecruiting at this site
- Zurich, SwitzerlandUniversitäts-Kinderspital ZürichRecruiting at this site
- Amiens, FranceCHU AmiensRecruiting at this site
- Angers, FranceChu AngersRecruiting at this site
- Besançon, FranceHôpital Jean MinjozRecruiting at this site
- Bordeaux, FranceHôpital des enfantsRecruiting at this site
- Brest, FranceChru BrestRecruiting at this site
- Caen, FranceCHU CAEN - Fédération de cancérologie - niveau 21Recruiting at this site
- Clermont-Ferrand, FranceCHU D'Estaing de CLERMONT FERRANDRecruiting at this site
- Dijon, FranceDIJON Hôpital d'enfantsRecruiting at this site
- Grenoble, FranceChu GrenobleRecruiting at this site
- Lille, FranceCentre Oscar LambretRecruiting at this site
- Lyon, FranceCentre Léon BérardRecruiting at this site
- Marseille, FranceHôpital d'Enfants de la TimoneRecruiting at this site
- Montpellier, FranceHôpital Arnaud de VilleneuveRecruiting at this site
- Nantes, FranceChr NantesRecruiting at this site
- Nice, FranceCHU NICERecruiting at this site
- Paris, FranceInstitut CurieRecruiting at this site
- Paris, FranceHôpital Armand TrousseauRecruiting at this site
- Reims, FranceChu ReimsRecruiting at this site
- Rennes, FranceChu Hopital SudRecruiting at this site
- Rouen, FranceHôpital Charles NICOLLERecruiting at this site
- Strasbourg, FranceHôpital Hautepierre-CHU StrasbourgRecruiting at this site
In total, worldwide, 35 of the 38 sites listed in the registry are recruiting; the other 3 are not currently recruiting.
Site status per the ClinicalTrials.gov registry (last update posted: July 22, 2025).
This status may have changed and says nothing about your eligibility: before taking any step, check with your oncologist or the site.
+ 5 more locations
See also
Other versions
These results are indicative and do not replace medical advice — discuss them with your doctor.